Deuterated Internal Standards

Many methods use an internal standard for quantitative analysis. An internal standard is used when performing bioanalysis with mass spectrometry detection.

Internal standards provide several advantages, e.g. minimizing or masking the variations resulting from sample preparation and extractions. An appropriate internal standard will therefore give a measure of control for extraction, HPLC injection and ionization variability. Generally, because of the abundance of hydrogen in organic molecules, the use of deuterium is preferred.

Synthetica can assist by synthesizing a deuterated version of the molecule you want to quantify and ensuring you an essential component for a robust high throughput bioanalytical method.